Mortality in Childhood-Onset Epilepsy

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Mortality in childhood-onset epilepsy.

OBJECTIVES To evaluate mortality in children with newly diagnosed epilepsy, to determine the risk of death, and to identify predictors of death from the point of diagnosis. DESIGN Prospective community-based cohort of 613 children with newly diagnosed epilepsy. The outcome measure was death. Chi2 Tests were used for bivariate analyses and the Cox proportional hazards model for multivariable a...

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Mortality risks in new-onset childhood epilepsy.

OBJECTIVES Estimate the causes and risk of death, specifically seizure related, in children followed from onset of epilepsy and to contrast the risk of seizure-related death with other common causes of death in the population. METHODS Mortality experiences from 4 pediatric cohorts of newly diagnosed patients were combined. Causes of death were classified as seizure related (including sudden u...

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Cognition in childhood-onset epilepsy.

In 1986, Ellenberg et al.2 reported that the IQ of a population based cohort of children with epilepsy at age 7 did not differ significantly from that of their siblings and that there was no decline between age 4 and 7. While there is still controversy whether there is any cognitive deterioration in most children, it has been increasingly recognized that, while the prognosis for seizure remissi...

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Remission of Childhood-onset Epilepsy

Investigators from the Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago IL and the Yale School of Medicine, New Haven, CT have conducted a prospective cohort study of 613 children with newly diagnosed epilepsy to evaluate the occurrence of complete remission and predictive factors. Of the 613 patients recruited, 516 were followed for greater than 10 years and of those, 328 (63.5%...

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Seizure clustering during drug treatment affects seizure outcome and mortality of childhood-onset epilepsy.

To provide evidence of whether seizure clustering is associated with drug resistance and increased mortality in childhood-onset epilepsy, a prospective, long-term population-based study was performed. One hundred and twenty patients who had been followed since disease onset (average age 37.0 years, SD 7.1, median 40.0, range 11-42; incident cases) were included. At the end of the follow-up peri...

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ژورنال

عنوان ژورنال: Archives of Pediatrics & Adolescent Medicine

سال: 2004

ISSN: 1072-4710

DOI: 10.1001/archpedi.158.12.1147